For decades, families affected by rare diseases have heard the same heartbreaking message: ‘There is no approved treatment yet.’ In 2026, that story is finally changing. From the first-ever approval for Menkes disease to a landmark FDA policy shift for gene therapies, the rare disease landscape is transforming at a pace never seen before. Here’s what you need to know.

A Practical lens for Board Members - Will this PI Founder still be CEO by Series B? Most European life sciences funds back companies where the founding CEO is a first‑time scientific leader: a PI out of a top lab, an ex‑pharma director, sometimes a computational founder with limited management experience. Very few investment memos say, “And we expect to replace them before Series B.” Yet that’s exactly what happens in a lot of cases—not always for the wrong reasons, but often

What the AI Research tells us vs what people are saying! If you read recent scientific reviews on artificial intelligence (AI) in the pharmaceutical industry, you get a clear message: AI is transforming drug discovery, clinical development, manufacturing, and safety.¹⁻⁵ If you talk to bench scientists, clinical teams, or data scientists over coffee, you often hear a more complicated story: pockets of impressive success, a lot of incremental improvements, and quite a few stall

On 23rd July, I’m officially launching Sharon Shields Consulting — a specialist consultancy focused on executive research, market mapping and talent intelligence for life sciences organisations across the UK, Europe and the US. I also partner with executive search consultancies who need deep, reliable research support for complex senior mandates.